Testicular Feminization in the Mouse: Studies of Leydig Cell Structure and Function1
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چکیده
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Advances in two techniques have made the problem of assessing the acute and/or chronic effects of toxic agents on Leydig cell structure and testosterone synthesis and secretion amenable to study. First, in vitro testicular perfusion has been perfected to a point where it closely resembles in situ testosterone secretion. Second, now it is possible to quantify the proportion of Leydig cell cytopl...
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After infection of male mice with the plerocercoids (spargana) of Spirometra mansoni, serum levels of estrogen and testicular weight were analyzed by enzyme-linked immunosorbent assay (ELISA) and weighing machine, respectively. The serum level of estrogen increased progressively in infected mice compared with normal controls, whereas the testicular weight of infected mice decreased significantl...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1973
ISSN: 0006-3363,1529-7268
DOI: 10.1093/biolreprod/9.1.9